Recovery of hypoglycemia symptoms after insulinoma negative pancreatic surgery: Case series (Published Online : september 28, 2017)
Mehmet Aziret1, Metin Ercan1, Adem Senturk1, Erdal Birol Bostanci2, Musa Akoglu2
1Sakarya University Faculty of Medicine, Department of General Surgery, Sakarya, Turkey
2Health Science University Ankaraya Yuksek Ihtisas Training and Research Hospital Department of Gastroenterological Surgery, Ankara, Turkey
Insulinoma, one of the most common endocrine tumors of the pancreas, is usually benign, solitary and has an intrapancreatic location. Precise localization of insulinoma is important for curative treatment.
This study looks at 5 patients who underwent operation for insulinoma. The median age, body mass index, preoperative insulin and C-peptide levels, and length of hospital stay were 36 years, 27 kg/m2, 32 μU/ml, 7ng/ml and 21 days, respectively. An endoscopic ultrasound (EUS) and intraoperative ultrasound (I-OUS) were conducted on all of the patients. Enucleation was performed on 3 patients and distal pancreatectomy ± splenectomy on 2 patients. Furthermore, the histopathological examination conducted on the patients showed insulinoma in 3 patients and granulomatous lymphadenitis in 1 patient, with one observed to have normal pancreas tissues. Following the operation, the glucose level of all patients was found to be within a normal range.
Distal pancreatectomy and enucleation can only be performed after determining precise localization of insulinoma via EUS and I-OUS.